Email : slokey@ucsc.edu

Originally hailing from Lubbock, TX, Scott spent his youth in the Southland. He moved to Marietta, GA at a young age before sauntering back to the great
state of Texas to the Plano/Dallas region where he remained for his High School years. Scott attended Trinity University, a small, Liberal Arts College in San
Antonio, TX. At Trinity Scott embraced the diverse range of classes that college offers and became enamored with both hard sciences like chemistry and
rich humanities such as philosophy.

Somewhere between refuting a philosophy professor’s portrayal of Buddhism and starting research in organometallic chemistry with Dr. Nancy Mills, Scott’s
passions began to coalesce around Chemistry and its related fields. The reward of sussing out solution to a problem in the lab and the thrill of discovery
kindled the passion for research that would eventually grow into a career. After his undergraduate work, Scott embarked on his PhD at UT Austin and joined
Dr. Brent Iverson’s research group where his research focused on the development of “pi-foldamers”, oligomers that fold in aqueous solution based on pi-
stacking interactions, and polyintercalating peptides.

After earning his PhD, Scott took a break from academia and traded in his southern drawl and cowboy boots for a backpack and ventured off on a solo,
Round-The-World trip. Scott visited exotic places such as Vietnam, Thailand, and India which Scott cites as being the most challenging and new culture he
St imbibed. Perhaps it was because of some persistent Kashmiri carpet salesmen that persuaded him to purchase a few fine rugs on his dad’s credit card or
perhaps it was the vastness of the people and geography, but after stopping by Dharmsala and hanging out with the Tibetans in exile, Scott made his way
back to familiarity via Cairo, Bulgaria, Munich and finally home.

Upon return to USA Scott began a Post Doc at Genentech in South San Francisco, CA where he continued to pursue computational and combinatorial
approaches to pharmaceutical challenges. His next Post Doc was at the newly formed Institute of Chemistry and Cell Biology at Harvard Medical School
where he worked with Dr. Timothy Mitchison in high-throughput screening endeavors.

In 2002 Scott made his way back to the West Coast, joined the chemistry faculty at UCSC, and started his own research lab. After settling into his new role
as Pl and professor, Scott began to accrue funding for a screening center for the department through the NIH and US State Department In 2007 the UCSC
Chemical Screening Center was born and has facilitated a number of high-throughput assays for his own group’s research as well as that of the other
members of the department. His research group focuses on understanding the complex relationship of stereochemistry and N-Methylation patterns as they
pertain to cell permeability and further, utilizing this relationship to create diverse and permeable drug scaffolds with exquisite selectivity that constrained
peptides offer.

Scott’s passion and genuine enthusiasm for Chemical Biology is as infectious as it is inspiring. As research continues, Scott seeks to solidify the Lokey Group
as a bastion of knowledge and creativity in the realm of constrained peptides.